optimisation of industrial parts by mesh morphing enabled automatic shape sculpting

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Crack Propagation Analysis of Near-Surface Defects with Radial Basis Functions Mesh Morphing

Abstract Fracture mechanics analysis is nowadays adopted in several industrial fields to assess the capability of components to withstand fatigue loads. Finite Element Method (FEM) is a well-established tool for the evaluation of flaw Stress Intensity Factors (SIF) and for the survey of its propagation. Nevertheless the study of the growth of near-surface circular and elliptical cracks is still an arduous task to be faced with FEM. In fact, the interaction of the flaw with free surfaces leads the crack front to assume complex shapes, whose simulation cannot be easily accomplished. A possible answer to deal with such a problem is to use the mesh morphing technique, a nodal relocation methodology, that allows to cover different problems. In fact, with mesh morphing, it is possible to fit the baseline flaw front with the desired shape (generic shape) and to automatically simulate its evolution at a certain number of cycles. In the proposed work this approach is demonstrated exploiting ANSYS Mechanical as FEM tool and RBF Morph ACT Extension as mesh-morpher. The results of the proposed workflow are compared with those available in literature

Pattern of care and effectiveness of treatment for glioblastoma patients in the real world: Results from a prospective population-based registry. Could survival differ in a high-volume center?

BACKGROUND: As yet, no population-based prospective studies have been conducted to investigate the incidence and clinical outcome of glioblastoma (GBM) or the diffusion and impact of the current standard therapeutic approach in newly diagnosed patients younger than aged 70 years. METHODS: Data on all new cases of primary brain tumors observed from January 1, 2009, to December 31, 2010, in adults residing within the Emilia-Romagna region were recorded in a prospective registry in the Project of Emilia Romagna on Neuro-Oncology (PERNO). Based on the data from this registry, a prospective evaluation was made of the treatment efficacy and outcome in GBM patients. RESULTS: Two hundred sixty-seven GBM patients (median age, 64 y; range, 29-84 y) were enrolled. The median overall survival (OS) was 10.7 months (95% CI, 9.2-12.4). The 139 patients 64aged 70 years who were given standard temozolomide treatment concomitant with and adjuvant to radiotherapy had a median OS of 16.4 months (95% CI, 14.0-18.5). With multivariate analysis, OS correlated significantly with KPS (HR = 0.458; 95% CI, 0.248-0.847; P = .0127), MGMT methylation status (HR = 0.612; 95% CI, 0.388-0.966; P = .0350), and treatment received in a high versus low-volume center (HR = 0.56; 95% CI, 0.328-0.986; P = .0446). CONCLUSIONS: The median OS following standard temozolomide treatment concurrent with and adjuvant to radiotherapy given to (72.8% of) patients aged 6470 years is consistent with findings reported from randomized phase III trials. The volume and expertise of the treatment center should be further investigated as a prognostic factor

Economia dei mercati e degli strumenti finanziari

Il libro analizza gli strumenti finanziari negoziati in Borsa, con particolare riferimento alle loro caratteristiche tecnico-economiche (comprese quelle fiscali) e alla loro valutazione nonché la struttura e il funzionamento dei mercati mobiliari italiani. Particolare attenzione viene dedicata all'analisi fondamentale degli strumenti finanziari il cui prezzo viene ricondotto al valore attuale dei flussi di cassa attesi. L'analisi del mercato primario e secondario degli strumenti finanziari viene svolta trattando, seppure in modo essenziale, gli aspetti regolamentari e approfondendo l'analisi della microstruttura dei mercati regolamentati italian

Appendice 2 - Questionario imprese

appendice al capitolo II "Le scelte di finanziamento e il rapporto banca-impresa nelle province di Modena e Reggio Emilia